C. elegans is a compact model to study fundamental principles that govern circuit assembly and function.​ We combine electron microscopy, genetics, optogenetics, and electrophysiology to address how its nervous system develops and operates. We apply tools and insights obtained from C. elegans studies to establish animal models to reveal circuit deficits underlying human neurological disorders.
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Preprints & Recent Publications

Connectomes across development reveal principles of brain maturation in C. elegans